Laboratory Record Keeping Procedures
Laboratory notebooks are the means for keeping a permanent record of the details of
an individual’s day-to-day research and development work in the laboratory or office.
They provide a basic reference which the individual and others can refer to a later
date; legal evidence with respect to the materials recorded, such as conception of
an invention and the date thereof or date of reduction to practice and test results;
in some instances compliance with the provisions of many grant and contractual arrangements.
Select a notebook with bound and numbered pages. This is extremely important. Loose-leaf
notebooks and tablets with tear out pages are not to be used. Each researcher should
have a separate notebook. Notebooks should not be shared
The UNO Bookstore can supply you with a high-quality, bound book entitled Laboratory Notebook. It is manufactured by Boorum & Pease Company (Esselte), order number L21150R. It contains a pre-printed version of these instructions as well as other desirable
user aids such as signature and witness lines on every page. This notebook is highly
If a less expensive notebook is required, The Bookstore can supply you with one entitled
Computation Notebook. It is manufactured by Avery Dennison, order number 43-648. A label can be obtained
from the IP Office (Wyly 1639) to designate this to be a Laboratory Notebook and to
record the necessary owner information. If the reader uses this book, a copy of these
written procedures should be taped to the inside of the front cover for future reference.
One drawback to this book is that it is quadrille printed rather than lined. And the
book does not include pre-printed signature and date line reminders on each page.
But it is bound and page numbered.
Instructions for Recording Data in the Laboratory Notebook
All entries should be made in a legible and orderly manner using permanent ink, preferably
black. Make entries clear and complete so that someone else could repeat the experiment
Avoid erasures. If an error is made, cross it out and make the correction immediately
thereafter. Cancellations or insertions should be initialed, dated and explained (in
the margin, if possible), by an appropriate notation.
Make sure the control page information is filled out prior to usage.
State the object and results of each experiment clearly and concisely. Give a complete,
factual and self-explanatory account of the progress of the work and the procedure
followed (reference to earlier work done by yourself or another maybe accomplished
by noting a previous page of the same notebook or the page and number of an earlier
notebook). All operating details and conditions should be reordered, indicating yields,
conversion, etc., and identifying products. Describe and give quantities of all materials
used. Explain all code numbers and abbreviations.
An entry dealing with a conception (invention, idea) should describe the thing conceived
(Example: whether it is a chemical compound, a combination of compounds, a combination
of a compound and a solvent, etc) as well as the utility for the thing conceived,
how it is to be used and the method(s) by which it is to be prepared, including equivalent
materials which could be used. Statements with regard to utility should be stated
positively. Work toward practical implementation of an invention should start as soon
as possible after disclosure in a notebook.
Negative or disparaging entries should be avoided. (Example: If a reaction was expected
to produce a 2% yield but instead produced 1%, do not state, “ Process does not work”).
Phraseology which expresses gratuitous comments or an opinion rather that a positive
statement and should be avoided. This is not an instruction to omit the conclusion
in an experiment, which had less that the expected results. Be factual.
Each day’s work should, whenever possible, be started on a separate page with lines
drawn angularly across the unused portion of the previous page. (This gives legal
evidence that additions were not made at a later date.) It is permissible, as stated
above, to make reference to an earlier page by reciting “Continued from page…” It
is extremely important that each page show the date of entry.
Each page must be signed and dated by the individual who makes the entry and does
the work. In addition, each page should be witnessed (signed and dated), using the
notation “Read and Understood”, preferably on the same day, but at least within one
week. The witness should not be connected with the conception, should not have taken
part in the experimental work performed by another, but should understand the technical
field of the entry. Record the project number and the record book number on each page.
Where two or more individuals make a conception, it need only be entered in the notebook
of one, but must be signed and dated by all the conceivers. Ideally, all conceivers
should sign on the same day.
For copying purposes, graphs, charts, analytical data, etc. should be attached to
the notebook pages with a permanent adhesive and should, when unfolded, be kept within
the confines of the opened notebook. No entries should be made on the page beneath attached sheets and nothing must be
obscured. Leave the heading at the top and the space provided for the witnessing signature
at the bottom of each page exposed. Inserts should be signed and dated by the person
making the entry and witnessed by another to provide the best legal evidence. If materials
such as spectra, graphs, etc. are not kept in the notebook, they must be signed, dated
and identified in such a manner as to provide a reference back to the pertinent page(s)
of the Laboratory Notebook itself.
Report the loss of theft of a research notebook.
Following the use of all the pages of each Laboratory Notebook, it should be sent
to the OTMC for record maintenance. Make sure that the table of contents page(s) are
complete or that a separate table of contents is supplied. After it has been recorded
it will be returned to the individual. An individual may retain, in his/her possession,
the Laboratory Notebook immediately preceding the one in which entries are currently
being made. Normally, the IP Office will keep all other Laboratory Notebooks. Authorized
individuals may check them out for reasonable lengths of time.